Lead author Dr. Wynn Meyer, along with the Clark and Chikina Labs, discusses how the loss of the PON1 gene in some marine mammals could leave them vulnerable to pesticides that seep into the sea.
Dr. Jianhua Xing discusses CRISPR and EMT in the latest edition of Research Insights on ResearchGate. Please click the link below for the full article.
Dr. Maria Chikina and associates contributed to a publication regarding a web-interface that provides access to a variety of tools for testing associations between epigenetic data samples.
Functional genomics assays produce sets of genomic regions as one of their main outputs. To biologically interpret such region-sets, researchers often use colocalization analysis, where the statistical significance of colocalization (overlap, spatial proximity) between two or more region-sets is tested. Existing colocalization analysis tools vary in the statistical methodology and analysis approaches, thus potentially providing different conclusions for the same research question. As the findings of colocalization analysis are often the basis for follow-up experiments, it is helpful to use several tools in parallel and to compare the results. We developed the Coloc-stats web service to facilitate such analyses. Coloc-stats provides a unified interface to perform colocalization analysis across various analytical methods and method-specific options (e.g. colocalization measures, resolution, null models). Coloc-stats helps the user to find a method that supports their experimental requirements and allows for a straightforward comparison across methods. Coloc-stats is implemented as a web server with a graphical user interface that assists users with configuring their colocalization analyses. Coloc-stats is freely available at https://hyperbrowser.uio.no/coloc-stats/.
Dr. Carvunis will be speaking as a part of the Senior Vice Chancellor’s Research Seminar. Her talk will be on June 29th, from 12:00 pm – 1:00 pm in Scaife Hall, Lecture Room 6.
For more information, please visit the SVC Seminar home page here.