Carlos Camacho, Ph.D.
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| Ph.D. in Physics, University of Maryland, College Park | |||||||||||||||||
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Research SummaryA striking set of specific and non-specific interactions encoded in the protein structure tolerates binding only to a unique substrate. My main research interests focus on modeling the physical interactions responsible for molecular recognition, and in the development of new technologies for structural prediction, their substrates and supramolecular assemblies. Any progress in these fundamental problems is bound to bring about a better understanding of how proteins work cooperatively in a cell, promoting breakthroughs in every aspect of the biological sciences. Recent PublicationsYe Z, Needham PG, Estabrooks SK, Whitaker SK, Garcia BL, Misra S, Brodsky JL, Camacho CJ (2017) Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase. Sci Rep. 7(1): 1789
Pabon NA, Camacho CJ (2017) Probing protein flexibility reveals a mechanism for selective promiscuity. eLife. 6: pii: e22889 Wingert BM, Oerlemans R, Camacho CJ (2017) Optimal affinity ranking for automated virtual screening validated in prospective D3R grand challenges. J Comput Aided Mol Des. Grants
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