Increasingly complex biological problems and extremely large biological data sets have necessitated new approaches to answer many of today’s current research challenges and tackle emerging questions in biology not amenable to traditional approaches. As one of the fields in the “New Biologies”, Computational and Systems Biology (CSB) encompasses an interdisciplinary approach that harnesses the power of computation and systems-level analyses to formulate and solve critical biological problems. These research programs within CSB also synergize and collaborate with the extensive basic and clinical research programs at the University of Pittsburgh and across the globe. Concomitant with our research foci, CSB is also a leader in educating and training all levels of emerging and nascent scientists, who will continue this work and identify and tackle new biological problems of the next generation.
Combination of Dynamical Systems Theory and Machine Learning Predicts Cell Fate Governing Equations
Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however, requires kinetic models capable of unveiling...
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Carvunis Lab Highlighted for Faculty-Postdoc Relationship Best Practices by Science
The Carvunis Lab was highlighted in an article in
Science for their outstanding relationship-building between faculty and postdocs...
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Article in The Atlantic highlights the work of the Bahar lab on MIS-C caused by SARS-CoV-2
This article highlights the work of the Bahar lab in collaboration with the Arditi lab on the molecular origin of multisystem inflammatory syndrome in children (MIS-C) observed in Covid-19...
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Lee Lab Publishes in Science Advances
A myriad of inflammatory cytokines regulate signaling pathways to maintain cellular homeostasis. The IkB kinase (IKK) complex is an integration hub for cytokines that govern nuclear factor kB (NF-kB) signaling. In response to inflammation, IKK is activated through recruitment to receptor-associated protein assemblies...
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Jianhua Xing Promoted to Professor
Congratulations to Dr. Jianhua Xing for his promotion to Professor!
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David Koes Promoted to Associate Professor
Congratulations to Dr. David Koes for his promotion to Associate Professor!
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NSF Graduate Research Fellowship Program offers awards to Caroline Larkin, April Rich and Gaby Gerlach
The 2021 NSF Graduate Research Fellowship Program (GRFP) has offered awards to Caroline Larkin (Faeder/Shoemaker Labs) and April Rich (Carvunis Lab), while Gaby Gerlach (Camacho Lab) has received an honorable mention. Congratulations!
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Samantha Furman awarded NIH NCI fellowship
Samantha Furman awarded NIH NCI F31 Ruth L. Kirschstein Predoctoral National Research Service Award to support her PhD work titled “Quantifying heterocellular communication and....
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Anne-Ruxandra Carvunis selected as a 2021 Alfred P. Sloan Research Fellow
Congratulations to Anne-Ruxandra Carvunis on being selected as a 2021 Alfred P. Sloan Research Fellow for her work in Computational & Evolutionary Molecular Biology....
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DCSB Welcomes Yu-Chih Chen to the faculty
It is with great pleasure that we welcome Dr. Yu-Chih Chen to our Department as an Assistant Professor in the tenure stream effective November 2020....
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