Shikhar Uttam

Shikhar Uttam, Ph.D.
Assistant Professor

Ph.D. Electrical Engineering (Minor: Mathematics) The University of Arizona, Tucson

Phone: (412) 383 7475

Research Summary

Primary focus: Computational imaging and optics, signal and systems, machine learning and imaging science applied to cancer systems biology, cancer epigenetics, early cancer detection, and precision medicine. Secondary focus: Computational biology and bioinformatics. Other interests: Radar imaging and quantum information theory.

Recent Publications
Uttam S, Hashash JG, LaFace J, Binion D, Regueiro M, Hartman DJ, Brand RE, Liu Y (2020) Three-Dimensional Nanoscale Nuclear Architecture Mapping of Rectal Biopsies Detects Colorectal Neoplasia in Patients with Inflammatory Bowel Disease Cancer Prevention Research. 12(8): 527-538

Uttam S, Stern AM, Furman S, Pullara F, Spagnolo D, Nguyen L, Gough AH, Sevinsky C, Ginty F, Taylor DL, Chennubhotla SC (2020) Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks Nature Communications. 11: 3515

Fouquerel E, Barnes RP, Uttam S, Watkins SC, Bruchez MP, Opresko PL (2019) Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis Molecular Cell. 75(1): 117 – 130