Developing embryos must orchestrate the fates and movements of their cells with precision. However, precise control is no easy feat; genetic mutations, unexpected environmental perturbations and noisy signaling all threaten to scramble communication. How do embryos ensure cells receive the right instructions? How are developmental mistakes corrected when they occur? Can we learn to engineer synthetic systems to have the reliability of developing embryos? The Lord lab will tackle these questions with a combination of synthetic biology, quantitative microscopy, computational modeling and classical embryology.
We’re a new and vibrant research group in the Department of Computational and Systems Biology at the University of Pittsburgh. We’re looking to build a diverse group of adventurous thinkers from quantitative and biological disciplines. Reach out if you’re interested!