Takis Benos

Panayiotis (Takis) V. Benos, Ph.D.
Professor and Vice Chair of Faculty Affairs

Molecular Biology, University of Crete, 1997
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Contact
Department of Computational and Systems Biology, SOM
University of Pittsburgh, SOM
3501 Fifth Ave., Suite 3064 BST3
Pittsburgh, PA 15260, U.S.A.

Phone: (412) 648-3315
E-mail: benos@pitt.edu
Website: http://www.csb.pitt.edu/Faculty/benos/

Research Summary

Our ultimate goal is to investigate the causes of chronic diseases and cancer by using all available data. Our work involves the development of new machine learning methods for the integration of multi-modal, large, biomedical datasets in a probabilistic graphical framework. For this purpose we collaborate with many clinical researchers in the University of Pittsburgh and elsewhere.

Recent Publications

Benos PV, Tosun BA, Manatakis DV, Vukmirovic M, Nguyen L, Yan X, Hu B, Deluliis G, Woolard T, Maya JD, Homer R, Kaminski N, Chennubhotla CS (2017) Towards Understanding Spatial Lung Tissue Heterogeneity In Idiopathic Pulmonary Fibrosis (IPF) A72. Mechanisms Driving Fibrosis A2384-A2384.

Pociask DA, Robinson KM, Chen K, McHugh KJ, Clay ME, Huang GT, Benos PV, Janssen-Heininger YM, Kolls JK, Anathy V, Alcorn JF (2017) Epigenetic and Transcriptomic Regulation of Lung Repair during Recovery from Influenza Infection. Am J Pathol.  [Epub ahead of print].

N. Olave, C.V. Lal, B. Halloran, K. Pandit, A.C. Cuna, O.M. Faye-Petersen, D.R. Kelly, T. Nicola, P.V. Benos, N. Kaminski, N. Ambalavanan, “Regulation of alveolar septation by microRNA-489?, Am J Physiol Lung Cell Mol Physiol, (2016), 10:L476-L487. PMCID:PMC4773841 Editor’s pick

 

Grants
Project title Proj Start Date Proj End Date Funding Source
Center for Causal Modeling and Discovery of Biomedical Knowledge from Big Data 9/29/2014 8/30/2018 NHGRI-U54
Integrative Graphical Models for Large Multi-Modal Biomedical Data 6/1/2015 5/31/2019 NLM-R01
Integrated Interdisciplinary, inter-university PhD Program Computational Biology (T32) 8/1/2014 7/31/2019 NIBIB-T32
Genomic Analysis of Tissue and Cellular Heterogeneity in IPF 8/14/2015 5/31/2019 NHLBI-R01
Probabilistic Causal Models for Melanoma Therapy Prognosis 3/1/2016 2/28/2017 P01CA121973-08
Systems Level Causal Discovery in Heterogeneous TOPMed Data 4/18/2017 3/31/2020 NIH-U01
Integrative Graphical Models for Large Multi-Modal Biomedical Data 6/1/2016 5/31/2019 NLM-R01
Immunoprevention and immunosurveillance of human non-viral cancers 8/1/2016 7/31/2019 NIH-R35
Integrated Interdisciplinary, inter-university PhD Program Computational Biology (T32) 8/1/2014 7/31/2019 NIBIB-T32