Announcing the Pittsburgh Revolution Fund

Advances in Quantitative Systems Pharmacology (QSP) in the Pittsburgh area are highlighted in a recent video, with the goal of bringing to the attention of the broader community the recent advances at Pitt, in collaboration with the UPMC, CMU and UPCI, and further promoting those activities through Pittsburgh Revolution Fund.

(click to view video)

The Fund, if  secured, will help aid collaborative and cross-disciplinary efforts in QSP approaches to enhance patient-driven therapies.

For more information:


For more information on these and other QSP programs currently in development at the University of Pittsburgh, please contact:
D. Lansing Taylor, PhD | 412-648-9200  |

To find out how to support The Revolution Fund and its efforts to enhance patient-driven therapies through QSP programs, please contact:
Jennifer Griffin | 412-623-2617 |

Announcing the First Annual Three Rivers Evolution Event (TREE)

We are excited to announce the first annual Three Rivers Evolution Event (TREE), a new regional conference serving Western Pennsylvania and the surrounding areas, sponsored in part by the American Society of Naturalists. Researchers of all stages and institution types are welcome. TREE will take place on Saturday, September 9th, 2017 at the University of Pittsburgh and include multiple sessions of talks, a poster session, and a keynote lecture presented by Dr. Cynthia Beall of Case Western University. The abstract deadline is July 14th, and we encourage those interested in presenting talks or posters to apply. Registration is accepted until September. Please see the website for more information: 

We hope to see you in September!

Cheng and Bahar Provide Novel Information About EAATs in eLife Publication

Identifying chloride channeling path in excitatory amino acid transporters

The paper provides novel evidence on the molecular determinants of the dual function, substrate transport and anion permeation, of excitatory amino acid transporters (EAATs).

It opens avenues toward illuminating how EAATs regulate synaptic transmission and neurological conditions.

This is a collaborative study between the Bahar and Amara (NIH) labs, with key contributions from Drs. Delany Torres-Salazar and Mary Cheng

Cheng MH#, Torres-Salazar D #, Gonzalez-Suarez AD, Amara SG & Bahar I*, “Substrate transport and anion permeation proceed through distinct pathways in glutamate transporters”. eLife, (2017).

Takis and Collaborators Receive U01 Grant

Systems Level Causal Discovery in Heterogeneous TOPMed Data

Takis Benos PhD, Frank Sciurba MD, and  Panos Chrysanthis PhD

The team will investigate the mechanism, pathology and pathophysiology of chronic obstructive pulmonary disease (COPD) facilitation and progression by analyzing existing TOPMed clinical and omics datasets. COPD is the third leading cause of death and a major cause of disability and health care costs in the US.  The tools and methods developed through this grant will be made publicly available using cloud services.

Congratulations, Takis!