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Akif Burak Tosun

Akif Burak Tosun, PhD
Research Instructor

PhD in Computer Engineering (Computer Science), Bilkent University, Turkey
Contact

3501 Fifth Avenue
Pittsburgh, PA 15260

Phone: (412) 383-5804
E-mail: tosun@pitt.edu

Website: Chakra Lab

Research Summary

I have been working in the field of computational pathology since 2006, starting with my Ph.D. work in unsupervised segmentation of colon cancer histopathological images. I joined University of Pittsburgh in Dr. Chennubhotla’s group to continue my work in computational pathology in the NIH BD2K funded effort: Center for Causal Discovery. My current work is focused on defining context aware features to represent lung, brain, colon, and breast tissue components and detect structural patterns that will help differentiate between normal and diseased tissue regions from whole slide images, as well as connect these patterns to genomic features to better understand the underling disease mechanisms. My research vision is to employ a quantitative approach that integrates computational pathology, systems biology, and the human visual and cognitive aspects to investigate and improve cancer research.

Recent Publications
Tosun AB, Nguyen L, Ong N, Navolotskaia O, Carter G, Fine JL, Taylor DL, Chennubhotla SC (2017) Histological detection of high-risk benign breast lesions from whole slide images, Medical Image Computing and Computer Assisted Intervention (MICCAI ‘17), Quebec, Canada, September 10-14, 2017, Proceedings, part 2, pp. 1444-152 .

Nguyen L, Tosun AB, Fine JL, Lee AV, Taylor DL, Chennubhotla SC (2017) Spatial statistics for segmenting histological structures in H&E stained tissue images. IEEE Trans Med Imaging. 36(7): 1522-1532