Dr. Xing (PI) and Dr. Simon Watkins (co-I) received a R01 award from NIDDK titled Role of the Snail1-Twist-p21 axis on cell cycle arrest and renal fibrosis development.
Kidney fibrosis is slowly-developing, largely irreversible process that accompanies all chronic kidney diseases. The team will use mathematical modeling and quantitative imaging approaches to study how the epithelial-to-mesenchymal transition and cell cycle program are coupled in kidney epithelial cells that lead to cell cycle arrest under acute kidney injury and subsequent fibrosis development.
|Dr. Jianhua Xing||Dr. Simon Watkins|