|
TIME |
TOPIC, SPEAKER |
9 9.15 am |
Introduction |
9.15 - 10.15 am |
SESSION I Nitric Oxide and Apoptosis Dr. Yoram Vodovotz (Surgery, UPMC) Dr. G. Bard Ermentrout (Math, Pitt) |
9.15 9.25 am |
Dr.
Yoram Vodovotz (Surgery, UPMC) Nitric oxide and apoptosis |
9.25 9.35 am |
Dr. G.
Bard Ermentrout (Math, Pitt) Modeling NO and apoptosis: theory and strategy |
9.35 10.00 am |
E.
Zerrin Bagci (CCBB, Pitt) Nitric oxide and apoptosis |
10.00 10.15 am | Discussion |
10.15 11.15 am |
Session
II DNA Damage Recognition and Signaling Dr. Richard Wood (UPCI and Pharmacology, Pitt) Dr. Ivet Bahar (CCBB, PItt) |
10.15 10.25 am |
Dr.
Richard Wood (UPCI and Pharmacology, Pitt) Function & mechanism of DDB: a protein from human cells that recognizes DNA damage |
10.25 10.35 am | Dr. John Rosenberg (Biol Sci, Pitt) |
10.35 10.45 am |
Dr. Vesna Rapic-Otrin (MGB, Pitt) From UV-DDB to Cullin-Containing Ubiquitin Ligase |
10.45 10.55 am | Discussion |
10.55 11.15 am | Dr. Baskaran Rajasekaran (MGB, Pitt) |
11.15 am 12.15 pm |
SESSION
III Signaling Ligands and Cascades Dr. John Lazo (Pharmacology, Pitt) Dr. Daniel Zuckerman (CCBB, Pitt) |
11.15 11.25 am |
Dr. John Lazo (Pharmacology, Pitt) Modeling ligand interactions with signaling molecules |
11.25 11.35 am |
Dr. Daniel Zuckerman (CCBB, Pitt) Docking and binding computations: an overview |
11.45 11.55 am |
Dr. Donald DeFranco (Pharmacology, Pitt) Opposing roles of MAPK and Akt signaling pathways on neuronal cell survival: importance of temporal and spatial parameters |
11.55 am 12.05 pm |
Dr. Dror Tobi (CCBB, Pitt) CDC25A / NSC663284 docking model |
12.05 pm 12.15 pm |
Dr. Billy Day (Pharmaceutical Sciences,
Pitt) Proteomics as a tool in drug discovery |
12.30 1.30 pm | LUNCH (Mellon Institute Social Room) |
1.30 2.30 pm |
SESSION
IV Integration Session (Multiscale Modeling) Dr. Joel Stiles (PSC/CMU) Dr. Jeffry Madura (Chem-Biochem, Duquesne) |
1.30 - 1.45 pm | Dr. Jeffrey Evanseck (Chem-Biochem, Duquesne) (Molecular) |
1.45 - 2.00 pm | Dr.
Joel Stiles (PSC/CMU) (Subcellular) Molecular-to-cellular modeling of complex biological processes |
2.00 - 2.15 pm |
Dr.
Shlomo Ta'asan (Math, CMU) (Cellular) A framework for multiscale modeling of biological systems |
2.15 - 2.30 pm | Panel Discussion |
2.30 3.30 pm |
SESSION
V Other Projects (membranes, signal transduction, hemoglobin) Dr. Michael Cascio (MGB, Pitt) Dr. Rob Coalson (Chem, Phys, Pitt) |
2.30 2.40 pm |
Dr. Roni
Rosenfeld (CS/LTI, CMU) Inferring property selection pressure from positional residue conservation |
2.40 2.50 pm |
Dr.
Michael Cascio (MGB, Pitt) Nicotinicoid Ion Channel Structure |
2.50 3.00 pm |
Dr.
Rob Coalson (Chem, Phys, Pitt) Modeling ion permeation through protein channels |
3.00 3.10 pm |
Dr.
Maria Kurnikova (Chem, CMU) Hierarchica approaches to modeling of ion channels and receptors |
3.20 3.20 pm |
Dr.
Jeffry Madura (Chem-Biochem, Duquesne) Bilayer simulations |
3.20 3.30 pm |
Dr.
Guillermo Romero (Pharmacology, Pitt) Protein-lipid interactions |
3.30 4.00 pm | Breakout Session |
4.00 4.30 pm | Concluding Remarks |
Questions/Comments regarding this workshop:
Dr. Michael Cascio, Chair, Pre-NPEBC Workshop Organizing Committee
Assistant Professor
Department. of Molecular Genetics & Biochemistry
School of Medicine, University of Pittsburgh
W1155 Biomedical Science Tower
Pittsburgh PA 1526
cascio@pitt.edu
office (412) 648-9488, fax (412) 624-1401,
lab (412) 383-9563
Dr. Ivet Bahar
Center for Computational Biology & Bioinformatics
Departmentof Molecular Genetics & Biochemistry
School of Medicine, University of Pittsburgh
Biomedical Science Tower, Rm W1043
200 Lothrop Street, Pittsburgh, PA 15261
Voice: 412 648 3332, Fax: 412 648 3163
bahar@pitt.edu | www.ccbb.pitt.edu | www.health.pitt.edu/pcbc
Dr. Joel Stiles
Associate Professor, Mellon College of Science & Pittsburgh Supercomputing Center
Carnegie Mellon University
Mellon Institute, Rm 220A
4400 Fifth Avenue, Pittsburgh, PA 15213
Voice: 412 268 4786, Fax: 412 268 8200
stiles@psc.edu | www.mcell.psc.edu
www.mcell.psc.edu/DReAMM | www.psc.edu/~stiles
Dr. Rajan Munshi, Pre-NPEBC Coordinator
Center for Computational Biology & Bioinformatics
University of Pittsburgh School of Medicine
W1044 Biomedical Science Center
200 Lothrop Street
Pittsburgh, PA 15261
rajan@pitt.edu | www.ccbb.pitt.edu | www.health.pitt.edu/pcbc
Tel: 412-648-7799, Fax: 412-648-3163