Yan’s dynamo ms submitted

https://www.biorxiv.org/content/10.1101/696724v2.full Single-cell RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however, requires dynamical models capable of predicting cell fate and unveiling the governing regulatory mechanisms. Here, we introduce dynamo, an analytical framework that reconciles intrinsic splicing and labeling…

Weikang’s first live cell studies of EMT accepted in Sci Adv.

Weikang Wang, Diana L. Douglas, Jingyu Zhang, Sangeeta Kumari, Metewo Selase Enuameh, Yan Dai, Callen T. Wallace, Simon C. Watkins, Weiguo Shu, Jianhua Xing, Live cell imaging and analysis reveal cell phenotypic transition dynamics inherently missing in snapshot data, BioRxiv copy, Science Advances, accepted. We hope to catch up the…

We received UPCI Pilot Award

We have been awarded a collaborative research award from the UPMC Hillman Developmental Pilot Program. The project title is “CRISPR-enabled tracking of cancer cell chromosome instability and karyotype landscape evolution”. The team includes Dr Xing (PI), Jian Yu (PI), Simon Watkins (Co-I), and Yijiun Chen (Co-I).