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BioNetGen
BioNetGen™ is software for the development and simulation of rule-based models of biochemical systems, including signal transduction, metabolic, and genetic regulatory networks.
The BioNetGen™ software package was initially developed by the Cell Signaling Team at Los Alamos National Laboratory. The current development team includes researchers in the Theoretical Division and Center for Nonlinear Studies at Los Alamos National Laboratory, the Departments of Biology and Computer Science at the University of New Mexico, the Department of Computational Biology at the University of Pittsburgh School of Medicine, the Center for Cell Analysis and Modeling at the University of Connecticut Health Center, and the Department of Biological Chemistry at the Johns Hopkins University School of Medicine.