Congratulations to Nick Pabon, PhD, for his first author paper in PlosCompBio

Dr. Nick Pabon publishes first author paper in PlosCompBio titled: “Predicting protein targets for drug-like compounds using transcriptomics” with Profs. Carlos J. Camacho and Ziv Bar-Joseph.

The paper describes the first method capable of predicting novel drug-target interactions using gene expression profiles. Nick contribution was specially notable in highlighting correlations between profiles indirectly related to the target as the main determinant of physical interactions in the machine learning model.

Read the full paper here

Pittsburgh Chromatin Club Mini-Symposium: 12/14

Friday December 14, 2018  1:00 – 5:00 PM UPMC Hillman Cancer Center, Cooper Classroom B/C

5115 Centre Avenue, Pittsburgh


1:00   Roni Lahr, Berman Lab, University of Pittsburgh School of Art & Sciences “The mTORC1-LARP1 axis in gene expression: Elucidating the molecular mechanism of La-related protein 1 in TOP translation.”

1:30   Miguel Brieno-Enriquez, University of Pittsburgh School of Medicine

“TERRA transcription and interacting proteins during PGC development”

2:00    Yi Shi, University of Pittsburgh School of Medicine

“Integrative proteomics to producing a large versatile repertoire of therapeutic nanobodies”

2:30    Refreshment Break

3:00    Joel McManus, Carnegie Mellon University “Finding and Testing Hidden uORFs”

3:30    Robin Lee, University of Pittsburgh School of Medicine

“Taking advantage of cell-to-cell variability to learn how cells process information.”

4:00   Jacob Stewart-Ornstein, Department of Computational and Systems Biology Research, Genome Stability Program, UPMC-Hillman Cancer Center

“Transcriptional linearity and dynamic feedback are hallmarks of stress responses from budding yeast to cancer.






Funding generously provided by the University of Pittsburgh, the Genome Stability Program at UPMC-Hillman Cancer Center, and the Microbiology and Molecular Genetics Department, University of Pittsburgh School of Medicine.

Organizers: Karen Arndt, Sanford Leuba, Ben Van Houten, and Andy VanDemark