Zoltan Oltvai, MD
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MD, Semmelweiss Medical University, Budapest | |
Contact3087 Biomedical Science Tower 3
3501 Fifth Avenue Pittsburgh, PA 15213 Phone: (412) 648-3333
E-mail: oltvai@pitt.edu Website: http://path.upmc.edu/personnel/faculty/oltvai.htm |
Research SummaryDr. Oltvai’s research interest is in the area of systems biology of cell metabolism, including the metabolism of prokaryotic and mammalian cells, including tumor cells. Dr. Oltvai is a staff pathologist in the Division of Clinical Microbiology. He is also a faculty member of the Interdisciplinary Biomedical Science Graduate Program, the Medical Scientist Training Program, the Cellular and Molecular Pathology Graduate Training Program, and the Joint CMU-Pitt PhD Program in Computational Biology. Recent PublicationsRashid, S.*, Long, Z.*, Singh, S., Kohram, M., Vashistha, H., Navlakha, S., Salman, H., Oltvai, Z.N. and Bar-Joseph, Z., (2019) Adjustment in tumbling rates improves bacterial chemotaxis on obstacle-laden terrains. Proc. Natl. Acad. Sci. U.S.A., 116: 11770-11775 Beckwitt, C.H., Clark, A.M., Ma, B., Whaley, D., Oltvai, Z.N. and Wells, A. (2018) Statins attenuate outgrowth of breast cancer metastases. Br. J. Cancer, 119: 1094–1105. Singh, M., Warita, K., Warita, T., Faeder, J.R., Lee, R.E.C., Sant, S. and Oltvai, Z.N. (2018) Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors. Sci. Rep., 8: 9388 Ishikawa, T., Hosaka, Y.Z., Beckwitt, C.H., Wells, A., Oltvai, Z.N. and Warita, K. (2018) Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics. Oncotarget, 9: 29304-29315. Raghu, V., Beckwitt, C.H, Warita, K., Wells, A., Benos, P.V. and Oltvai, Z.N., (2018) Biomarker identification for statin sensitivity of cancer cell lines. Biochem. Biophys. Res. Comm., 495: 659-665. Liu, B., Oltvai, Z.N., Bayir, H., Silverman, G.A., Pak, S.C., Perlmutter, D.H. and Bahar, I. (2017) Quantitative assessment of cell fate decision between autophagy and apoptosis. Sci. Rep., 7:17605 Long, Z., Quaife B, Salman, H. and Oltvai, Z.N. (2017) Cell-cell communication enhances bacterial chemotaxis toward external attractants. Sci. Rep., 7:12855 |