Journal Articles
- Spagnolo DM, Gyanchandani R, Al-Kofahi Y, Stern AM, Lezon TR, Gough A, Meyer DE, Ginty F, Sarachan B, Fine J, Lee AV, Taylor DL, Chennubhotla SC. Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers.J Pathol Inform 7:47 (2016).
- Erdem C, Nagle AM, Casa AJ, Litzenburger BC, Wang Y, Taylor DL, Lee AV and Lezon TR. Proteomic screening and lasso regression reveal differential signaling in insulin and insulin-like growth factor I pathways. Mol Cell Proteomics 15:3045-3057 (2016).PMID: 27364358
- Gough A, Chen N, Schurdak M, Shun TY, Lezon T, Boltz R, Reese C, Wagner J, Vernetti L, Grandis J, Lee A and Taylor DL. Identifying and Quantifying Heterogeneity in High Content Analysis: Application of Heterogeneity Indices to Drug Discovery. PLoS ONE 9:e102678 (2014).PMID: 4103836
- Bakan A, Dutta A, Mao W, Liu Y, Chennubhotla C, Lezon TR and Bahar I. Evol and ProDy for bridging protein sequence evolution and structural dynamics. Bioinformatics 30:2681-2683 (2014). PMID: 24849577
- Lezon TR and Bahar I. Constraints imposed by the membrane selectively guide the alternating access dynamics of the glutamate transporter GltPh. Biophys J 102:1331-1340 (2012).
PMID: 22455916
- Lezon TR. The effects of rigid motions on elastic network model force constants. Proteins 80:1133-1142 (2012).
PMID: 22228562
- Lezon TR and Bahar I. Using entropy maximization to understand the determinants of structural dynamics beyond native contact topology. PloS Comp Biol 6:e1000816 (2010).
PMID: 20585542
- Bahar I, Lezon TR, Bakan A and Shrivastava IH. Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins. Chem Rev 110:1463-1497 (2010).
PMID: 19785456
- Bahar I, Lezon TR, Yang L-W and Eyal E. Global dynamics of proteins: Bridging between structure and function. Ann Rev Biophys 39:23-32 (2010).
PMID: 20192781
- Lezon TR, Sali A and Bahar I. Global motions of the nuclear pore complex: insights from elastic network models. PLoS Comp Biol 5: e1000496 (2009).
PMID: 19730674
Science Editor's Choice
Supporting Material
- Lezon TR, Banavar JR, Cieplak M, Maritan A and Fedoroff NV. Using the principle of entropy maximization to infer genetic interaction networks from gene expression patterns. Proc Natl Acad Sci USA 103:19033-19038 (2006).
PMID: 17138668
- Lezon TR, Banavar JR and Maritan A. The origami of life. J Phys: Condens Matter 18:847-888 (2006).
- Banavar JR, Cieplak M, Flammini A, Hoang TX, Kamien RD, Lezon TR, Marenduzzo D, Maritan A, Seno F, Snir Y and Trovato A. Geometry of proteins: hydrogen bonding, sterics and marginally compact tubes. Phys Rev E. 73:031921 (2006).
PMID: 16605572
- Lezon TR, Banavar JR, Lesk AM and Maritan A. What determines the spectrum of protein native state structures? Proteins 63:273-277 (2006).
PMID: 16470841
- Lezon T, Banavar JR and Maritan A. Recognition of coarse-grained protein tertiary structure. Proteins 55:536-547 (2004).
PMID: 15103618
Book Chapters
- Gough A, Lezon T, Faeder JR, Chennubhotla C, Murphy RF, Critchley-Thorne R and Taylor DL. High-content analysis with cellular and tissue systems biology: A bridge between cancer cell biology and tissue-based diagnostics, in The Molecular Basis of Cancer. Edited by Mendelsohn J, Gray JW, Howley PM, Israel MA and Thompson CB. Elsevier, 2014.
- Zomot E, Bakan A, Shrivastava IH, DeChancie J, Lezon TR and Bahar I. Sodium-coupled secondary transporters: insights from structure-based computations, in Molecular Machines. Edited by Roux B. World Scientific, 2011.
- Lezon TR, Shrivastava IH, Yang Z and Bahar I. Elastic network models for biomolecular dynamics: Theory and application to membrane proteins and viruses, in Handbook on Biological Networks. Edited by Boccaletti S, Latora V and Moreno Y. World Scientific, 2009.
- Lezon TR, Banavar JR, Cieplak M, Fedoroff NV and Maritan A. The most probable genetic interaction networks inferred from gene expression patterns, in Analysis of Microarray Data: A Network-Based Approach. Edited by Dehmer M and Emmert-Streib F. Wiley, 2008.