Summary of Research
Our ultimate goal is to investigate the molecular mechanisms that are implicated in chronic diseases and developmental processes. Our work involves the development of new computational and statistical models for the study of gene expression regulation (protein coding and non-coding genes) in a systems' biology framework.
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Panayiotis (Takis) Benos, PhD
Associate Professor Website: www.benoslab.pitt.edu
Research Area
Computational Genomics, Systems Biology
Recent Publications
Milosevic J, Pandit K, Magister M, Rabinovich E, Ellwanger DC, Yu G, Vuga LJ, Weksler B, Benos PV, Gibson KF, Macmillan M, Kahn M, Kaminski N (2012). Profibrotic Role of miR-154 in Pulmonary Fibrosis.” Am J Respir Cell Mol Biol.
Watters RJ, Benos PV, Oesterreich S. (2012). To bind or not to bind - FoxA1 determines estrogen receptor action in breast cancer progression. Breast Cancer Res. 14: 312. Kadri S, Hinman V, Benos PV. (2011). RNA deep sequencing reveals differential microRNA expression during development of sea urchin and sea star. PLoS One. 6:e29217.
Zhang Y, Handley D, Kaplan T, Yu H, Bais AS, Richards T, Pandit KV, Zeng Q, Benos PV, Friedman N, Eickelberg O, Kaminski N. (2011). High Throughput determination of TGFb1/SMAD3 targets in A549 lung epithelial cells. PLoS One, 6(5): e20319.
Huang GT, Athanassiou C, Benos PV. (2011). mirConnX: condition-specific mRNA-microRNA network integrator. Nucleic Acids Res. 39: W416-23.
Publications
Awards and Honors
2007-current: elected member, Faculty of 1000
Contact
Department of Computational and Systems Biology, SOM
University of Pittsburgh, SOM
3501 Fifth Ave., Suite 3064 BST3
Pittsburgh, PA 15260, U.S.A.
Phone: (412) 648-3315
E-mail:
Website: www.benoslab.pitt.edu
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