Announcing the First Annual Three Rivers Evolution Event (TREE)

We are excited to announce the first annual Three Rivers Evolution Event (TREE), a new regional conference serving Western Pennsylvania and the surrounding areas, sponsored in part by the American Society of Naturalists. Researchers of all stages and institution types are welcome. TREE will take place on Saturday, September 9th, 2017 at the University of Pittsburgh and include multiple sessions of talks, a poster session, and a keynote lecture presented by Dr. Cynthia Beall of Case Western University. The abstract deadline is July 14th, and we encourage those interested in presenting talks or posters to apply. Registration is accepted until September. Please see the website for more information: https://sites.google.com/view/tree2017/home 

We hope to see you in September!

CSB – Immuno Joint Departmental Retreat

The Department of Computational and Systems Biology and Department of Immunology hosted a joint retreat on June 7, 2017 at The Twentieth Century Club in Pittsburgh, PA.

Speakers included:

  • Keynote – Dr. Steve Kleinstein (Yale)
  • Anne-Ruxandra Carvunis (CSB)
  • Bill Hawse (Immuno)
  • Takis Benos (CSB)
  • Lisa Borghesi (Immuno)
  • Carlos Camacho (CSB)
  • Florian Weisel (Immuno)
  • Chakra Chennubhotla (CSB)
  • Sandra Cascio (Immuno)
  • Jim Faeder (CSB)
  • Dario Vignali (Immuno)

A poster session followed – congratulations to our winners!
GRADUATE STUDENTS:
1st place: Abigail Overacre-Delgoffe (Immuno)
2nd place: Marta Wells (CSB)
3rd place: Jingyu Zhang (CSB)

POSTDOCS and RESEARCH ASSOCIATES:
1st place: Deepali Sawant (Immuno)
2nd place: Jason Lohmueller (Immuno)
3rd place: Justin Spiriti (CSB)

Later in the evening, the Department of Computational and Systems Biology had a reception with awards at the Carnegie Science Center.

Congratulations to Wynn Meyer (best postdoc), She Zhang (best student), and Marcia Schwab (best staff) on their awards.

More info here: http://csb.pitt.edu/retreat/

Photos: http://www.csb.pitt.edu/csb-retreat-2017/

Cheng and Bahar Provide Novel Information About EAATs in eLife Publication

Identifying chloride channeling path in excitatory amino acid transporters

The paper provides novel evidence on the molecular determinants of the dual function, substrate transport and anion permeation, of excitatory amino acid transporters (EAATs).

It opens avenues toward illuminating how EAATs regulate synaptic transmission and neurological conditions.

This is a collaborative study between the Bahar and Amara (NIH) labs, with key contributions from Drs. Delany Torres-Salazar and Mary Cheng

Cheng MH#, Torres-Salazar D #, Gonzalez-Suarez AD, Amara SG & Bahar I*, “Substrate transport and anion permeation proceed through distinct pathways in glutamate transporters”. eLife, (2017).

CSB Members Attend March for Science

Pitt’s Computational and Systems Biology showed up to the March for Science in style – both in Pittsburgh and DC!
There was a demonstration in Oakland from 12 PM – 2 PM, beginning on Bigelow Blvd between Forbes and Fifth Aves. There were several speakers both before and after the march around Oakland.

One of the speakers was adjunct faculty member, Lance Davidson, and he talked about how science is part of Pittsburgh’s core.

Takis and Collaborators Receive U01 Grant

Systems Level Causal Discovery in Heterogeneous TOPMed Data

Takis Benos PhD, Frank Sciurba MD, and  Panos Chrysanthis PhD

The team will investigate the mechanism, pathology and pathophysiology of chronic obstructive pulmonary disease (COPD) facilitation and progression by analyzing existing TOPMed clinical and omics datasets. COPD is the third leading cause of death and a major cause of disability and health care costs in the US.  The tools and methods developed through this grant will be made publicly available using cloud services.

Congratulations, Takis!