2017

NF-κB Dynamics Discriminate between TNF Doses in Single Cells
Q Zhang, S Gupta, DL Schipper, GJ Kowalczyk, AE Mancini, JR Faeder, REC Lee
Cell Systems

Demystifying the cytokine network: Mathematical models point the way
PA Morel, REC Lee, JR Faeder
Cytokine


2016

NF-κB signalling and cell fate decisions in response to a short pulse of tumour necrosis factor
REC Lee, MA Qasaimeh, X Xia, D Juncker, S Gaudet
Scientific Reports 6


2015

Putting it all on pigmentation: Heuristics of a bold and stochastic cell fate decision

J Xing and REC Lee
Sci. Signal. 06 Oct 2015: Vol. 8, Issue 397, pp. fs17


2014

Fold Change of Nuclear NF-κB Determines TNF-Induced Transcription in Single Cells

REC Lee, SR Walker, K Savery, DA Frank, S Gaudet
Molecular cell 53 (6), 867-879

Cell-to-cell variability in cell death: can systems biology help us make sense of it all?

X Xia, MS Owen, REC Lee, S Gaudet
Cell death & disease 5, e1261-e1261

Monitoring the Proteostasis Function of the Saccharomyces cerevisiae Metacaspase Yca1

A Shrestha, REC Lee, LA Megeney
Caspases, Paracaspases, and Metacaspases, 223-235


2013

A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts

JDR Knight, R Tian, REC Lee, F Wang, A Beauvais, H Zou, LA Megeney, AC Gingras, T Pawson, D Figeys, R Kothary
Skelet Muscle 2 (5)

 


2010

Metacaspase Yca1 is required for clearance of insoluble protein aggregates

REC Lee, S Brunette, LG Puente, LA Megeney
Proceedings of the National Academy of Sciences 107 (30), 13348-13353

 


2009

Reconstructing regulatory kinase pathways from phosphopeptide data: a bioinformatics approach

LG Puente, REC Lee, LA Megeney
Phospho-Proteomics, 311-319

 


2008

A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics

REC Lee, LG Puente, M Kærn, LA Megeney
PLoS One 3 (8), e2956

 


2006

Reconstructing the regulatory kinase pathways of myogenesis from phosphopeptide data

LG Puente, S Voisin, REC Lee, LA Megeney
Molecular & Cellular Proteomics 5 (12), 2244-2251

 


2005

The yeast kinome displays scale free topology with functional hub clusters

REC Lee, LA Megeney
BMC bioinformatics 6 (1), 271

 


Robin E. C. Lee on Pubmed